Background: PIK3CA pathways are the most frequently mutated oncogenic pathway in head and neck squamous cell carcinoma (HNSCC), including virally driven HNCs.PIK3CA is involved in the PI3K-PTEN-mTOR signalling pathway.PIK3CA has been implicated in HNSCC progression and PIK3CA mutations may serve as predictive biomarkers for therapy selection.Circul
The analysis of the secondary texts obtained as a result of a linguistic experiment has allowed the author to create a degree classification for the Speaker Grille emergence of metalinguistic consciousness and to compare them to personalization and depersonalization tendencies.The classification, as well as various metaindicators, linguistic and ex
The energy transition towards increased electric power production from renewable energy (RE) resources creates new challenges to ensure the stability of power grids.In conventional power grids voltage fluctuations can be controlled locally.Here, it is explored whether this may be changed by the energy transition.It is well established that the incr
Gliomas are brain tumors originated from glial cells.The most frequent form of glioma is the glioblastoma BUTTERCUP BLOND PWD (GB).This lethal tumor is frequently originated from genetic alterations in epidermal growth factor receptor (EGFR) and PI3K pathways.Recent results suggest that signaling pathways, other than primary founder mutations, play